Toremifene and the liver
Toremifene and the liver: metabolism via CYP3A4, changes in liver enzymes, comparison with tamoxifen, steatosis, interactions and monitoring of ALT/AST. An editorial overview with sources.
Training
Programs, exercise technique and load planning.
Fluoxymesterone (halotestin) and the musculoskeletal system
Fluoxymesterone and the musculoskeletal system: the effect of androgens on bones, the role of estrogen, closure of growth plates in adolescents, the risk of tendon rupture and the myth of “dry joints.”
Testosterone propionate and hair: the risk of androgenetic alopecia
Testosterone propionate and hair: the role of DHT and 5α-reductase in androgenetic alopecia, the significance of genetics, the Hamilton–Norwood scale, body hair growth and treatment methods confirmed by studies.
Selenium or Zinc: what is the difference
Selenium and zinc: how these trace elements differ in biological role, sources, forms, intake norms and overdose risks. A comparative editorial overview with references to studies.
Creatine or HMB: what is the difference
Creatine or HMB: how they differ in origin, mechanism of action, evidence base and safety. A comparison from our editors with references to studies.
Beta-alanine for women: are there any peculiarities
Beta-alanine for women: the carnosine level in female muscles, studies in women, tingling and dosing adjusted for body weight, pregnancy, menopause, myths and practical advice.
Interaction of Insulin with other drugs
Interaction of insulin with other drugs: what enhances hypoglycemia, what raises glucose, which drugs mask symptoms, the role of alcohol, corticosteroids, beta-blockers, GLP-1 and anabolic substances.
The history of the drug Nebivolol
The history of nebivolol: from James Black’s propranolol to third-generation beta-blockers, development at Janssen, the discovery of NO-mediated vasodilation and the SENIORS study.
The history of the discovery of Tesamorelin
The history of tesamorelin: from the discovery of GHRH and the modification of the full molecule to phase III studies in patients with HIV, FDA approval in 2010 and new directions of research.
Stanozolol and the kidneys: what is known about the load
How stanozolol and anabolic steroids in general affect the kidneys: FSGS, cholemic nephropathy, pressure, creatinine and cystatin C. What is known from studies and what is not. An editorial overview.
Toremifene and the liver
Toremifene and the liver: metabolism via CYP3A4, changes in liver enzymes, comparison with tamoxifen, steatosis, interactions and monitoring of ALT/AST. An editorial overview with sources.
Fluoxymesterone (halotestin) and the musculoskeletal system
Fluoxymesterone and the musculoskeletal system: the effect of androgens on bones, the role of estrogen, closure of growth plates in adolescents, the risk of tendon rupture and the myth of “dry joints.”